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KMID : 0605720160220030196
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Journal of the Korean Society of Biological Therapies in Psychiatry
2016 Volume.22 No. 3 p.196 ~ p.208
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Characteristics of Neurocognitive Function and Factors Affecting the Severity of Neurocognitive Disorders Classified according to Subtypes
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Lee Seung-Woo
Seo Wan-Seok
Cheon Eun-Jin
Kim Hye-Guem
Lee Young-Ji
Bai Dai-Seg
Lee Dong-Yeop
Koo Bon-Hoon
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Abstract
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Objectives：To assess differences in the cognitive function of patients with neurocognitive disorders, and to investigate cognitive tests that affect the severity classification of neurocognitive disorders.
Methods：We retrospectively examined 207 patients diagnosed as having a neurocognitive disorder due to Alzheimer disease(AD), vascular neurocognitive disorder(VD), or neurocognitive disorder due to traumatic brain injury (TBI), per the Diagnostic and Statistical Manual of Mental Disorders, fifth edition(DSM-5). We administered the Seoul Neuropsychological Screening Battery, second edition. Patients were classified into major and mild neurocognitive disorder groups according to the DSM-5 diagnostic criteria and clinical dementia rating score.
Results：The major VD group exhibited greater impairment on attention function, language function, visuospatial function, and frontal and executive function than the major AD group. The major TBI group exhibited greater impairment on language function, memory function, and frontal and executive function than the major AD group. The mild VD group exhibited greater impairment on visuospatial function, and frontal and executive function than the mild AD group. Results of logistic regression analyses showed that the Korean-Boston Naming Test and memory function tests affected the severity classification of neurocognitive disorders.
Conclusion：Despite our study’s limitations, the VD and TBI groups exhibited greater impairment on overall neurocognitive function than the AD group. Additionally, the Korean-Boston Naming Test and memory function tests can significantly affect the severity classification of neurocognitive disorders.
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KEYWORD
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Neurocognitive disorder, Alzheimer disease, Vascular dementia Traumatic brain injury
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